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FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

This product is solely intended for research purposes as a chemical compound. Its designation permits its use exclusively for in vitro testing and laboratory experimentation. All information regarding this product provided on our website is purely educational. By law, any form of bodily introduction of this product into humans or animals is strictly prohibited. It should only be handled by professionals who are licensed and qualified. This product is neither a drug, food, nor cosmetic, and must not be misrepresented, misused, or mislabeled as such.

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CAS 42464-96-0
5-Amino-1MQ
20mg Box(2 x 10mg vials)
Purity 99% HPLC
RUO Research use only
Not for human or veterinary use.
5-Amino-1MQ 10mg research peptide vial, 99%+ purity, research use only

5-Amino-1MQ (10mg vials)

Price:
$56.00 – $195.00
Vendor:
Allen Biotechnology Co
Quantity (mg)

$56.00

5-AMINO-1MQ

5-Amino-1MQ, also written as 5-amino-1-methylquinolinium, is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in metabolic research. It is studied for its effects on cellular NAD+ availability, adipocyte metabolism and energy expenditure in preclinical models.

Product Format10mg vials
Vial Size10mg
Vial Capacity3 mL
Box Combinations20mg, 50mg, 100mg
Cost per milligram$1.95 – $2.80
Multi-vial Purity99.66%
Endotoxin ScreeningPASSED
Heavy Metals ScreeningPASSED
Purity ScreeningPASSED
Doubly ValidatedYES
Independently TestedYES

Allen Biotechnology Co Manufacturer ID: WF63
Batch ID: AM202648
CAS: 42464-96-0
Molecular Formula: C10H11IN2

Research Studies

(for educational purposes only)

NNMT inhibition in diet-induced obesity models

Preclinical work on methylquinolinium NNMT inhibitors, including 5-amino-1-methylquinolinium, reported high membrane permeability and selectivity for NNMT. In cultured adipocytes, NNMT inhibition reduced intracellular 1-methylnicotinamide, increased NAD+ and SAM, and suppressed lipogenesis. In diet-induced obese mice, systemic treatment was associated with reduced body weight, white adipose mass and adipocyte size without changes in total food intake within the study window.

In plain English

This is the core animal and mechanism research area for 5-Amino-1MQ. The compound is studied as an NNMT inhibitor — not an appetite suppressant. The mouse data are promising, but they are preclinical and do not establish human outcomes.

NNMT, NAD+ salvage and metabolic disease

Review literature summarizes evidence linking NNMT activity to obesity and type 2 diabetes biology. NNMT methylates nicotinamide using S-adenosylmethionine, which can alter NAD+ salvage chemistry, methyl-donor balance, and downstream energy-metabolism pathways. NNMT knockdown or inhibition has been associated with increased energy expenditure and improved insulin-sensitivity markers in animal and cellular studies.

In plain English

These reviews place 5-Amino-1MQ inside the larger NNMT research landscape and make clear that the strongest evidence is still preclinical.

5-Amino-1MQ — Frequently asked questions

What is 5-Amino-1MQ?

5-Amino-1MQ, also written as 5-amino-1-methylquinolinium, is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in metabolic research. It is sold strictly for laboratory research use — not for human or veterinary use.

What purity is this 5-Amino-1MQ?

The current batch tested at 99.66% by HPLC at an independent laboratory, with additional endotoxin, heavy-metals and sterility screening. Certificates are published per batch on our Independent Certifications page.

What sizes does 5-Amino-1MQ come in?

5-Amino-1MQ (10mg vials) is offered in 20mg, 50mg, 100mg boxes (2 × 10mg vials, 5 × 10mg vials, 10 × 10mg vials), priced $56.00 to $195.00 — the per-mg cost falls as box size increases.

How should 5-Amino-1MQ be stored?

Keep sealed lyophilized vials refrigerated at 2–8°C away from light (stable 24+ months). After reconstitution with bacteriostatic water, refrigerate and use within the study-validated window, typically 30 days; never freeze reconstituted solution.

Related products

Not suitable for human consumption – intended for research only

Thank you for choosing Allen Biotechnology Co.

NOTICE: All information provided above is strictly intended for educational and informational purposes. Our products are designed for research use solely and are not approved for human consumption. Please refrain from any form of ingestion.

By making a purchase from Allen Biotechnology Co, you acknowledge that you are acquiring Research Chemicals. Our products are exclusively intended for laboratory research purposes.

It is imperative that only qualified and licensed professionals handle this product. Under no circumstances should it be utilized as a drug, agricultural or pesticide product, food additive, or household chemical. Misrepresentation of this product for such purposes is strictly prohibited by law. All content on our website is provided for educational use exclusively. Any form of introduction into the human or animal body is illegal.

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