hGH fragment 176-191 and lipid metabolism
Preclinical studies of the C-terminal growth hormone fragment reported stimulation of lipolysis and inhibition of lipogenesis in adipose tissue models, without the IGF-1 elevation or insulin resistance associated with intact growth hormone. Rodent studies in obese models described reductions in body fat under chronic administration.
In plain English
Researchers isolated the part of growth hormone thought to drive fat metabolism and studied it separately. Animal data suggest it keeps the lipolytic activity while avoiding growth effects — human evidence remains limited.